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1 article(s) from Colley, Helen Elizabeth

Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

Sabrina Barbosa de Souza Ferreira,
Gustavo Braga,
Évelin Lemos Oliveira,
Jéssica Bassi da Silva,
Hélen Cássia Rosseto,
Lidiane Vizioli de Castro Hoshino,
Mauro Luciano Baesso,
Wilker Caetano,
Craig Murdoch,
Helen Elizabeth Colley and
Marcos Luciano Bruschi

Beilstein J. Nanotechnol. 2019, 10, 2304–2328, doi:10.3762/bjnano.10.222

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Figure 1: Emission spectra of systems containing 0.01% (w/w) P407, 1.6 × 10⁻⁴% (w/w) C974P and 1.8 × 10⁻⁵ mol...

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Figure 2: Incorporation kinetic profiles of systems containing poloxamer 407 (P407), Carbopol 974P (C974P) an...

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Figure 3: Fluorescence emission spectra and K_sv determination by Equation 3 of CUR (3.6 × 10⁻⁵ mol/L) at 25 °C (A and B...

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Figure 4: SEM micrographs of systems containing 15% (w/w) P407, 0.25% (w/w) C974P: without CUR original magni...

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Figure 5: TEM images of nanostructured systems at 37 °C demonstrating the individual micellar organization: (...

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Figure 6: Flow rheograms of formulations containing 15% (w/w) P407, 0.25% (w/w) C974P (∆ - green) and 15% (w/...

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Figure 7: (A) Elastic modulus, G’ (Pa), (B) viscous modulus, G” (Pa), (C) dynamic viscosity, η’ (Pa), and (D)...

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Figure 8: Textural properties of the systems containing P407, C974P and CUR, investigated at 25 and 37 °C: (A...

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Figure 9: (A) Cumulative retention profile of a polymeric system containing poloxamer 407, Carbopol 974P^® and...

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Figure 10: Release profile of CUR from a mucoadhesive nanostructured system containing 15% (w/w) P407, 0.25% (...

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Figure 11: Optical absorption spectra obtained from PAS with (A) CUR and polymeric systems with and without CU...

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Figure 12: Cytotoxicity of formulations: (A) cell survival curves of drug and formulations, (B) IC₅₀ compariso...

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Figure 13: Schematic presentation of the rheological analysis setup utilized for continuous shear (flow) and o...

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Figure 14: Schematic presentation of the setup utilized for ex vivo liquid falling mucoadhesion tests.

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Figure 15: Schematic presentation of the modified Franz’s cell used for the in vitro curcumin release measurem...

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Published 25 Nov 2019

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